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In contrast, when injected with XCL1-OT-I plus poly(I:C), tumour growth was significantly inhibited at day 18 (Fig

In contrast, when injected with XCL1-OT-I plus poly(I:C), tumour growth was significantly inhibited at day 18 (Fig.?5b). fusion protein plus poly(I:C) showed suppressive effects on tumour growth in synergy with anti-PD-1 Ab. Conclusions Cancer Ag targeting to XCR1+ DCs should be a promising procedure as a combination anticancer?therapy with immune checkpoint blockade. mice were generated […]

We also treated cells with the Ca2+ ionophore known as ionomycin as a positive control since calcineurin can be activated by an increase in intracellular calcium

We also treated cells with the Ca2+ ionophore known as ionomycin as a positive control since calcineurin can be activated by an increase in intracellular calcium. of DEX. Only 1 1 day of DEX treatment was sufficient to trigger a sustained increase in mRNA that lasted for 4 days after the removal of DEX. Similar […]